Associate Professor of Surgery
- Consultant Urological Surgeon
I trained in Bristol and worked in Exeter and Bath before coming to Oxford in 1983 to do research in renal transplantation under the direction of Professor Sir Peter Morris. I was awarded my DPhil in 1986 and after a clinical lecturer post in urology and transplantation was appointed consultant urological and transplant surgeon in 1991. My special interest is in renal cancer and the urological complications of transplantation with a national referral for some patients needing complex renal cancer surgery.
In 1992, I set up a research programme with Professor Adrian Harris, Director of the Cancer Research Unit in Oxford, and have co-supervised many research students who have carried out work in investigating bladder and kidney cancer. Several have won international awards for their work.
I have been clinical director of the High Intensity Focused Ultrasound (HIFU) unit since 2002.
I am author of 18 book chapters and over 100 peer reviewed publications.
High Intensity Focused Ultrasound is a novel way of treating solid tumours using a non-invasive technique to cause local ablation. HIFU also has applications in other areas such as delivering drug therapy and vascular occlusion, as well as the potential for enhancing anti-tumour immunity. Oxford has established itself as one of the leading international academic centres for clinical HIFU research. The research programme initially centred on the HIFU unit at the Churchill Hospital, and is now expanding into a number of laboratory based projects around the University in both the translational and clinical setting.
The Blokeology podcast
Professor David Cranston comes talks about prostate cancer and PSA testing on the Blokeology podcast. Listen to the podcast here.
High-intensity focused ultrasound treatment of liver tumours: post-treatment MRI correlates well with intra-operative estimates of treatment volume.
Leslie T. et al, (2012), Br J Radiol, 85, 1363 - 1370
PSA testing: a personal view.
Cranston D., (2019), Br J Gen Pract, 69
Tumour seeding of the renal tumour biopsy tract - a histologically under-recognised feature?
Macklin PS. et al, (2019), Histopathology
A review of high intensity focused ultrasound in relation to the treatment of renal tumours and other malignancies.
Cranston D., (2015), Ultrason Sonochem, 27, 654 - 658
Active surveillance of small renal masses offers short-term oncological efficacy equivalent to radical and partial nephrectomy
Patel N. et al, (2012), BJU International, 110, 1270 - 1275
Active surveillance of small renal masses offers short-term oncological efficacy equivalent to radical and partial nephrectomy.
Patel N. et al, (2012), BJU Int, 110, 1270 - 1275