Dr Jessica Scaife
Contact information
07989192975
situ.development@nds.ox.ac.uk
Dr Jessica Scaife Development Lead, Surgical Intervention Trials Unit (SITU) Nuffield Department of Surgical Sciences (NDS), University of Oxford Botnar Research Centre, Old Road, Headington, Oxford OX3 7HE
Dr
Research groups
Jessica Scaife
PhD
Development Lead, NDS SITU
Development Lead
I oversee all aspects of the development of funding applications as they progress through our EOI pathway.
I have over twenty years experience designing experimental paradigms. A Neuropsychopharmacologist and Cognitive Neuroscientist, my research combines neuroimaging, electrophysiology and stimulation to investigate the neural and pharmacological basis of reward and emotion. During my 20 year postdoctoral career, I investigated brain function in both patient populations and healthy volunteers, using MRI and MEG. I ran studies in experimental medicine, Phase 1 and 3 clinical trials, including deep brain stimulation with Alex Green. I use mixed methods research to capture the lived experience of patients.
A member of the MSD PPI network, I lead PPI throughout trial development, and beyond, I am committed to developing and fostering greater connections with patient partners and charities.
I am passionate about public engagement and encouraging students to consider careers in STEM through events and work experience.
Recent publications
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Effects of ulotaront on brain circuits of reward, working memory, and emotion processing in healthy volunteers with high or low schizotypy.
Journal article
Perini F. et al, (2023), Schizophrenia (Heidelb), 9
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Catechol-O-methyltransferase activity does not influence emotional processing in men.
Journal article
Martens MA. et al, (2022), J Psychopharmacol
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Deep brain stimulation of the nucleus accumbens in severe enduring anorexia nervosa: a pilot study
Journal article
SCAIFE J. et al, (2022), Frontiers in Behavioral Neuroscience
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A Longitudinal Magnetoencephalographic Study of the Effects of Deep Brain Stimulation on Neuronal Dynamics in Severe Anorexia Nervosa.
Journal article
Braeutigam S. et al, (2022), Front Behav Neurosci, 16
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Translating the promise of 5HT4 receptor agonists for the treatment of depression.
Journal article
Murphy SE. et al, (2021), Psychol Med, 51, 1111 - 1120