Oxford Transplant Centre, Churchill Hospital, Oxford, OX3 7LE
I studied medicine at Cambridge and St Thomas’s Hospital and after qualifying trained as a surgeon in London and Cambridge before undertaking a period of research at the University of Cambridge under the supervision of Professor Sir Roy Calne.
In 1988 I was appointed Visiting Assistant Professor of Surgery at Indiana University Medical Center, USA, where I was responsible for initiating a programme of liver transplantation. I returned to the UK in 1989 to take up the post of University Lecturer (honorary consultant) in the University Department of Surgery at Cambridge. I was the Clinical Director of the Cambridge Transplant Unit and also a Fellow and Director of Studies in Medicine at Magdalene College, Cambridge. I was appointed to my current post in 1999.
Professor of Transplantation
- Consultant Transplant and HPB Surgeon
- Director Oxford Transplant Centre
My experimental interest is in the application of isolated perfusion of the liver to a number of therapeutic areas. In particular, perfusion of the liver with oxygenated blood at normal body temperature can allow recovery from damage, extended preservation for transplantation and organ specific delivery of therapy.
Clinical research studies include small scale pilot studies of novel immunosuppressive strategies and the organisation of a multi centre national trial.
Impaired O2 unloading from stored blood results in diffusion-limited O2 release at tissues: evidence from human kidneys
Dumbill R. et al, (2023), Blood
Normothermic Machine Perfusion of Donor Livers for Transplantation in the United States: A Randomized Controlled Trial.
Chapman WC. et al, (2023), Ann Surg, 278, e912 - e921
Machine perfusion of the liver and bioengineering
Schlegel A. et al, (2023), Journal of Hepatology, 78, 1181 - 1198
Honoring the gift: The transformative potential of transplant-declined human organs.
Albert C. et al, (2023), Am J Transplant, 23, 165 - 170
Enhanced recovery for liver transplantation: recommendations from the 2022 International Liver Transplantation Society consensus conference.
Pollok JM. et al, (2023), Lancet Gastroenterol Hepatol, 8, 81 - 94