I studied medicine at Cambridge and St Thomas’s Hospital and after qualifying trained as a surgeon in London and Cambridge before undertaking a period of research at the University of Cambridge under the supervision of Professor Sir Roy Calne.
In 1988 I was appointed Visiting Assistant Professor of Surgery at Indiana University Medical Center, USA, where I was responsible for initiating a programme of liver transplantation. I returned to the UK in 1989 to take up the post of University Lecturer (honorary consultant) in the University Department of Surgery at Cambridge. I was the Clinical Director of the Cambridge Transplant Unit and also a Fellow and Director of Studies in Medicine at Magdalene College, Cambridge. I was appointed to my current post in 1999.
Professor of Transplantation
- Consultant Transplant and HPB Surgeon
- Director Oxford Transplant Centre
My experimental interest is in the application of isolated perfusion of the liver to a number of therapeutic areas. In particular, perfusion of the liver with oxygenated blood at normal body temperature can allow recovery from damage, extended preservation for transplantation and organ specific delivery of therapy.
Clinical research studies include small scale pilot studies of novel immunosuppressive strategies and the organisation of a multi centre national trial.
Ischemia-reperfusion injuries assessment during pancreas preservation
Prudhomme T. et al, (2021), International Journal of Molecular Sciences, 22
Effect of utilizing more than 20-year older deceased donor kidneys for young recipients: An analysis of the uk registry
Vrakas G. et al, (2021), Experimental and Clinical Transplantation, 19, 405 - 410
Outcomes after simultaneous pancreas-kidney transplantation from donation after circulatory death donors: a UK registry analysis.
Callaghan CJ. et al, (2021), Am J Transplant
Design, Analysis, and Pitfalls of Clinical Trials Using Ex Situ Liver Machine Perfusion: The International Liver Transplantation Society Consensus Guidelines.
Martins PN. et al, (2021), Transplantation, 105, 796 - 815
Coagulation Factors Accumulate During Normothermic Liver Machine Perfusion Regardless of Donor Type and Severity of Ischemic Injury.
Gilbo N. et al, (2021), Transplantation