Contact information
LOCATION:
NHS Blood and Transplant (NHSBT) Blood Donor Centre, John Radcliffe Hospital, Oxford, OX3 9BQ
Richard Dumbill
BA MBBS MRCS DPhil
Academic Clinical Fellow and Registrar in General Surgery (Transplantation)
I began my medical education at Balliol College, Oxford (2010-13) where I obtained an undergraduate degree in Medical Sciences, before moving to University College London to complete my clinical studies (MBBS with distinction, 2013-2016). I moved back to Oxford for an Academic Foundation Program followed by Core Surgical training. I then completed a DPhil in Surgical Sciences at the University of Oxford (2020-2023, supervised by Professors Peter Friend and Simon Knight), running a first-in-human trial of prolonged Normothermic Machine Perfusion (NMP) of the kidney prior to transplantation (Normothermic Kidney Perfusion Phase 1, NKP1). This trial was funded by the National Institute for Health Research and hosted by the Oxford Transplant Centre, and was awarded the British Transplant Society’s Medawar Medal for best clinical paper in 2023.
I subsequently secured a post-doctoral NIHR Academic Clinical Fellowship, and currently divide my time between transplantation research and higher surgical training. My particular areas of interest and expertise are in the use of NMP in kidney transplantation for ex-situ organ assessment and treatment. Having demonstrated safety and feasibility during NKP1, we are now planning phase 2 trials to examine efficacy and the utility of NMP as a platform for viability assessment.
Recent publications
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Prolonged normothermic perfusion of the kidney – a historically controlled, phase 1 cohort study
Preprint
Dumbill R. et al, (2024)
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Impaired O2 unloading from stored blood results in diffusion-limited O2 release at tissues: evidence from human kidneys.
Journal article
Dumbill R. et al, (2024), Blood, 143, 721 - 733
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Seven decades of organ transplantation: Out of the 20th and into the 21st century
Journal article
Dumbill R. and Sinha S., (2024), Journal of Indira Gandhi Institute of Medical Sciences, 10, 3 - 5
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Diffusion-limited O2release in human kidneys perfused with stored blood
Preprint
Dumbill R. et al, (2023)
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Ureterorenoscopy during normothermic machine perfusion: effect of varying renal pelvis pressure.
Journal article
Dumbill R. et al, (2023), BJU Int, 131, 50 - 52
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Transplant and Recipient Factors in Prediction of Kidney Transplant Outcomes: A UK-Wide Paired Analysis.
Journal article
Dumbill R. et al, (2022), J Clin Med, 11