Contact information
LOCATION
Radiobiology Research Institute, Churchill Hospital, Headington, Oxford
Research groups
Collaborators
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Clare Verrill
Professor of Cellular Pathology and Artificial Intelligence
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Ian Mills
John Black Professor of Prostate Cancer, Interim Head of Department, Group Leader
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Freddie Hamdy CBE
Head of Department
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Alastair Lamb
Associate Professor
Valentine Macaulay
MD, PhD, FRCP
Emeritus Associate Professor
- Honorary Consultant in Medical Oncology
Val qualified as a doctor at Charing Cross Hospital Medical School and trained in Medical Oncology at the Royal Marsden Hospital London and Churchill Hospital Oxford. Following a PhD with Alan Ashworth at Chester Beatty Laboratories in London, her postdoctoral training was supported by MRC Clinician Scientist and Cancer Research UK Senior Clinical Fellowships and HEFCE Clinical Senior Lectureship. She was Associate Professor and Honorary Consultant in Medical Oncology, Department of Oncology, University of Oxford from 2001 to 2021. Since 2021, Val was Emeritus Associate Professor, Nuffield Department of Surgical Sciences, University of Oxford. Her laboratory research group uses basic, translational and clinical research to investigate the role of IGFs in prostate cancer and is supported by collaborating clinicians and scientists in Oxford and elsewhere.
Recent publications
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GeneFEAST: the pivotal, gene-centric step in functional enrichment analysis interpretation
Preprint
TAYLOR A., (2023)
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A Phase Ib/II study of IGF-neutralising antibody xentuzumab with enzalutamide in metastatic castration-resistant prostate cancer.
Journal article
Macaulay VM. et al, (2023), Br J Cancer
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WNT5A-ROR2 axis mediates VEGF dependence of BRAF mutant melanoma.
Journal article
Coupe N. et al, (2023), Cell Oncol (Dordr), 46, 391 - 407
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CHK1 inhibition exacerbates replication stress induced by IGF blockade
Journal article
Macaulay V. et al, (2021), Oncogene
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IGF-1R nuclear import and recruitment to chromatin involves both alpha and beta subunits.
Journal article
Mills JV. et al, (2021), Discov Oncol, 12