Contact information
+44 (0) 1865 221271
Oxford Transplant Centre, Churchill Hospital, Oxford, OX3 7LE
Research groups
Collaborators
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Simon Knight
Associate Professor of Transplant Surgery
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James Hunter
Associate Professor of Transplant Surgery
![]() | Professor of Cell Physiology |
External Collaborators
Professor Sue Francis, Professor of Physics, University of Nottingham
Professor David Long, Professor in Paediatric Nephrology, University College London
Dr Edward Sharples, Oxford University Hospitals NHS Foundation Trust
Dr Helen Weavers, Associate Professor in Cell and Developmental Biology, University of Bristol
Dr Katie Mylonas, Kidney Research UK (KRUK) Senior Research Fellow (with the Thompson Family Charitable Trust) and Principal Investigator, University of Edinburgh
Professor Valeria Mas, Professor of Surgery, Professor of Microbiology and Immunology, and a cellular and molecular transplant immunologist, University of Maryland, USA
Professor Rikke Norregaard, Professor of Translational Nephrology, University of Aarhus, Denmark
Maria Kaisar
Associate Professor of Transplantation Science
Dr Maria Kaisar is an Associate Professor of Transplantation Science at the Nuffield Department of Surgical Sciences (NDS), University of Oxford, and Scientific Programme Lead for Organ Donation and Transplantation at NHS Blood and Transplant. She holds the roles of National Scientific Coordinator and Executive of the Quality in Organ Donation project. Her scientific focus is on organ donation and transplantation with a translational purpose in improving donor organ assessment and transplant outcomes.
Following completion of her DPhil in Transplantation Science at NDS, she went on to lead her multidisciplinary team as a Principal Investigator. By integrating advanced multi-omics technologies with big data analytics and biostatistics Maria’s research team focuses on identifying and validating biomarkers that more accurately reflect donor organ quality, viability, and resilience. By combining molecular profiling, imaging, and computational approaches, her group aims to uncover the mechanisms of organ injury and the biological resilience of cells and tissues, seeking to develop refined tools of donor organ assessment so more organs are transplanted that last for longer in transplant recipients.
Research highlights
Maria is the Principal Investigator of the ADMIRE project, funded by the Stoneygate Trust and Garfield Weston Foundation, and supported by Kidney Research UK. ADMIRE aims to develop non-invasive markers that can be measured during donor management to assess donor kidneys prior to transplantation by integrating donor plasma protein profiles and clinical variable using machine learning methodologies.
As Chief Investigator, Maria leads a collaborative team across Oxford, Nottingham, and UCL to test the feasibility of integrating ex vivo and post-transplant MRI into routine clinical pathways. This has led to the first-in-human clinical study of ex vivo MRI scanning of donor kidneys prior to transplantation, followed by a three-month MRI scan of recipients post-transplant, combining MRI and 3D histology
Her work has opened new scientific directions by characterising the protein degradome in donor kidneys — the landscape of protein degradation driven by dysregulated enzymatic activity during biological dysregulation during deceased donation.
Leadership positions
Co-Chair of Research Committee, Nuffield Department of Surgical Sciences, University of Oxford (2024 – present)
Chair of Basic Science Committee at European Society of Organ Transplantation (2023-2025)
Councillor of Transplant Science at the British Transplant Society (2022- 2025)
Key publications
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Proteomic Profiles of Deceased Donor Kidney Biopsies Obtained Prior to Transplantation Correlate with Allograft Function at One Year
Other
Kaisar M. et al, (2017), AMERICAN JOURNAL OF TRANSPLANTATION, 17, 366 - 367
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Regional heterogeneity of cellular prion protein isoforms in the mouse brain.
Journal article
Beringue V. et al, (2003), Brain, 126, 2065 - 2073
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Proteomes of Deceased Donor Kidneys Exhibit Age- Moderated Associations with Transplant Outcomes
Conference paper
Charles P. et al, (2023), AMERICAN JOURNAL OF TRANSPLANTATION, 23, S633 - S633
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Oxygenated versus standard cold perfusion preservation in kidney transplantation (COMPARE): a randomised, double-blind, paired, phase 3 trial.
Journal article
Jochmans I. et al, (2020), Lancet, 396, 1653 - 1662
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Transplant and Recipient Factors in Prediction of Kidney Transplant Outcomes: A UK-Wide Paired Analysis.
Journal article
Dumbill R. et al, (2022), J Clin Med, 11
Recent publications
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Improving outcomes in kidney transplantation through advances in donor organ perfusion.
Journal article
Hunter J. et al, (2025), Nat Rev Nephrol, 21, 818 - 832
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Association between hyperglycaemia, diabetes complications and development of fibrotic conditions among people living with type 1 and type 2 diabetes in England: a retrospective cohort study using UK Clinical Resource Datalink Aurum and Hospital Episode Statistics.
Journal article
Massen GM. et al, (2025), BMJ Open, 15
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The association between fibrotic diseases and treatment resistant hypertension in England.
Journal article
Massen GM. et al, (2025), Eur J Prev Cardiol
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Can Pretransplant Donor Cystatin-C Identify High-Risk Kidneys? Insights into Grafts with Primary Non-Function and Long-Term Transplant Outcomes
Conference paper
Michelakis IE. et al, (2025), AMERICAN JOURNAL OF TRANSPLANTATION, 25
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Metabolomic Signatures of Perfused Livers Reveal Early Evaluation May Be Superior
Conference paper
Fortier A. et al, (2025), AMERICAN JOURNAL OF TRANSPLANTATION, 25, s29 - s29
