Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Preserving livers at body temperature has been shown to improve transplant success and to increase the number of viable donor livers available for transplant, which could lead to shorter waiting lists for patients and lower mortality rates.

Preserving livers at body temperature has been shown to improve transplant success and to increase the number of viable donor livers available for transplant.

The research, published in the journal Nature, is the first multinational randomized study of its kind comparing conventional cold storage in an ice box with a technique called normothermic machine perfusion in 220 liver transplant patients. The device used for normothermic machine preservation was developed by OrganOx Ltd, a MedTech business spun-out from the University of Oxford as a result of a collaboration between Professor Peter Friend (Nuffield Deparmtent of Surgical Sciences) and Professor Constantin Coussios (Institute of Biomedical Engineering). 

Dr David Nasralla, lead author of the study, said: ‘This research has the potential to profoundly improve liver transplants globally.'

Find out more (University of Oxford website)

Read the coverage on BBC Health News

 

Further coverage

'Warm transplants' save livers and lives
Nature, 18/04/2018

"Warm Transplants" Save Livers and Lives
Scientific American, 19/04/2018

Machine transforms transplants by keeping livers alive outside of body for up to 24 hours
The Sun, 19/04/2018

Keeping donated livers warm could improve transplants
New York Post, 20/04/2018

New Organ Preservation Device Keeps Livers Alive Longer and Better for Transplantation
Medgadget, 20/04/2018

 

Similar stories

Genetic mapping of tumours reveals how cancers grow

Researchers from the University of Oxford, KTH Royal Institute of Technology, Science for Life Laboratory, and the Karolinska Institutet, Solna, Sweden, have found that individual prostate tumours contain a previously unknown range of genetic variation.

Two NDS researchers receive prestigious MRC Clinical Research Training Fellowships

Miss Catherine Lovegrove and Dr Alexander Sagar from the Nuffield Department of Surgical Sciences (NDS) have been awarded highly competitive Clinical Research Training Fellowships by the Medical Research Council (MRC).

WHO Classification of Tumours programme awarded large grant to improve classification and evidence base

A new project titled Mapping the Evidence for the World Health Organization (WHO) Classification of Tumours: A Living Evidence Gap Map by Tumour Type (WCT EVI MAP), led by researchers of the WHO Classification of Tumours programme at the International Agency for Research on Cancer (IARC), has received a grant of €3.5 million from the European Commission. This four-year project, which will be undertaken in collaboration with six other international institutions, including Oxford University's Nuffield Department of Surgical Sciences (NDS), was launched on 1 July 2022.

Blog posts

Oxford MedSci goes silver: 10 Years of Athena SWAN

The Medical Sciences Division is celebrating 10 years since its first Athena Swan bronze application, and the first year in which all 16 of its departments have achieved a silver award. The silver award recognises commitment to gender equality, understanding culture and context, and more. Read about our department’s hard work and innovation.

Lights, camera, action! My journey into video production

Dr Hannah McGivern provides a 'behind-the-scenes' account of her experience producing the video 'Journey of a QUOD Sample: Donating to Transplant Research', supported by the funds from the University of Oxford Public Engagement with Research (PER) Seed Fund.

Mentoring in practice

NDS has launched a new, interdepartmental mentoring scheme called RECOGNISE. In this podcast, Gemma Horbatowski (HR Advisor) interviews Monica Dolton (Programme Manager and Research Project Manager) about her experiences of mentor-mentee relationships.