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Oxford Radcliffe Biobank (ORB) logo

Prostate cancer cellsThe following table shows a representative list of projects for which ORB / OCHRe have provided, or are providing, samples and/or services.

Project Title

ORB / OCHRe Involvement

Pre-operative window of opportunity study of the effects of atovaquone on hypoxia in non-small cell lung carcinoma (ATOM trial)Biobank support provided to process 810 fresh tissue samples into FFPE blocks from 23 cases. Project duration three years to date.
SMP2 Stratified Medicine ProgrammeProvision of unstained sections and blood samples from patients recruited to research study.
Validation of single cell sequencing technique for pancreatic cancer specimensConsenting of patients and sample collection for research project
The impact of cancer microenvironment on the quality of tumor-infiltrating T cellsConsenting of patients and collection of fresh lung samples for issue to researcher – project duration three to five years
Gynaecological Oncology Targeted Therapy Study 01 (GO-Target-01) - IF method developmentIdentification of patients, consent checking and provision of FFPE samples – 13 cases provided over two year period.
Evolution and heterogeneity across multiple cancer types_5 year project – patient consent and venepuncture (blood sampling), sample collections from Churchill and John Radcliffe Hospitals, freezing of sample and provision of frozen sections. Staining and scanning of sections.
Immune cell interactions in inflammatory diseasesOngoing since 2014 - collection of fresh tonsils. 44 samples collected to date
Multi-modal Analysis of Longitudinally Sampled Oesophageal Cancer Patients - CRUK OeCa CollectionCRUK oesophageal collection – Emma can provide more details regarding what she does – tracking samples / consenting / collecting etc. Two year project
Analysis of the Interaction between epithelial cells, mast cells and basophils in patients with asthma and healthy controls69 fresh lung samples issued to research project – ongoing since 2016
Prostate Molecular Targeting to Enhance surgery using IR800 IAB2M (ProMOTE IR800 IAB2M)Frozen and FFPE samples collected and stored by ORB
The Role of Neutrophils in the Development of Liver MetastasisNow closed but an example of another tissue type – 125 fresh liver samples issued to research project between 2014–17
Identification of new targets for a lung cancer vaccineCollection and freezing of 54 lung tissue samples from 12 patients
Investigating cellular changes and potential biomarkers within colorectal cancer14 samples collected from seven patients under ORB consent