Opened in 2006
£1.2 million state of the art facility
Isolating human islets for clinical transplant and research
Here at the DRWF Human Islet Isolation Facility we isolate high quality human islets for both clinical and research use
Welcome to the DRWF Human Islet Isolation Facility. Our facility is located within the Churchill Hospital in Oxford. We provide human islets for clinical transplantation and for a broad range of research projects. In addition, the isolation team and associated research group continue to investigate ways of improving the efficiency of islet isolation. This webpage provides information about our £1.2 million state of the art facility, as well as an introduction into our clinical and research islet provision. Finally, you can take a look at some of the innovative research that goes on within our group, which is aimed at improving human islet isolation and transplantation outcomes.
About the facility
Human Islet Isolation
HTA Licensing
Clinical Islet Provision
Research Islet Provision
Islet Isolation Research
Director and HTA Designated Individual
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Paul Johnson
Director of Oxford Islet Isolation and Islet Transplant Programmes and Professor of Paediatric Surgery
Our Team
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Daniel Brandhorst
Senior Researcher
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Heide Brandhorst
Senior Postdoctoral Scientist
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Rebecca Spiers
Islet Facility Manager
Selected publications
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Strategies to Improve the Oxygen Supply to Microencapsulated Islets.
Journal article
Brandhorst D. et al, (2020), Transplantation, 104
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Donor age significantly influences the Raman spectroscopic biomolecular fingerprint of human pancreatic extracellular matrix proteins following collagenase-based digestion.
Journal article
Spiers RM. et al, (2019), Acta Biomater, 99, 269 - 283
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Comparison of Clostripain and Neutral Protease as Supplementary Enzymes for Human Islet Isolation.
Journal article
Brandhorst H. et al, (2019), Cell Transplant, 28, 176 - 184
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Intussusception
Journal article
Bradshaw CJ. and Johnson PRV., (2019), Surgery (United Kingdom), 37, 216 - 220