Life in the balance: How protein quality control governs health and disease
Dr Dimitrios Doultsinos, Nuffield Department of Surgical Sciences, Oxford University
Outreach Public event Research
Thursday, 21 January 2021, 7.30pm to 8pm
Live Stream on ATOM Society YouTube channel
Every cell in our body exists as part of a hugely sophisticated machinery that strives to prolong life. Our cells must work optimally under stressful conditions and be able to overcome challenges. These stresses arise with every little change of our environment (like eating lunch or exercising) and cells adapt to these stresses through quality control mechanisms. In the first part of this talk we will see how these same mechanisms govern the manifestation of disease using cancer and neurodegeneration as examples. In the second part we will have a look at the diverse landscape of disciplines needed to design a new drug, the challenges behind targeting these quality control mechanisms to combat disease and how a clinical trial for such a medicine is designed.