Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

A team of scientists, including Dr David Nasralla and Professor Peter Friend from the Nuffield Department of Surgical Sciences, have had their research featured on the cover of the prestigious journal Nature.

They found that preserving livers at body temperature helps to improve transplant success and to increase the number of viable donor livers available for transplant, which could lead to shorter waiting lists for patients and lower mortality rates.

In the first randomized study of its kind, the Consortium for Organ Preservation in Europe (COPE) clinical trial team at NDS compared conventional cold storage in an ice box with a technique called normothermic machine perfusion in 220 liver transplant patients. The device used for normothermic machine preservation was developed by OrganOx Ltd, a MedTech business spun-out from the University of Oxford as a result of a collaboration between Professor Friend and Professor Constantin Coussios (Institute of Biomedical Engineering).

NatureDr David Nasralla, who is lead author of the study, said: 'Having our work published by a journal as prestigious as Nature is a wonderful achievement and also a testament to the huge amount of work that went into this study and the two decades of dedication from Professor Friend and Professor Coussios that preceded it. Being featured on the front cover of the journal is a great privilege and unexpected honour that I think any academic could only dream of.'

The research appears in the 3 May 2018 edition of Nature.

The research was also recently featured as a news article on the University of Oxford website and BBC Health News.

Similar stories

Omair Shariq wins Best Clinical Paper at the American Association of Endocrine Surgeons 2021 Annual Meeting

Dr Omair Shariq, a DPhil student and clinical research fellow in the Nuffield Department of Surgical Sciences (NDS) and Oxford Centre for Diabetes Endocrinology and Metabolism (OCDEM), has received the 2021 Best Presentation for Clinical Research award during the 41st Annual Meeting of the American Association of Endocrine Surgeons (AAES), which was held virtually on 25-27 April 2021.

Artificial intelligence tool for streamlining pathology workflow

A multidisciplinary team, comprising Andrea Chatrian, Dr Richard Colling, Professor Clare Verrill, Professor Jens Rittscher and colleagues, develops an algorithm for automated requesting of additional investigation in diagnostically uncertain prostate biopsies.

Latest issue of JNDS now online

The latest issue of the Journal of the Nuffield Department of Surgical Sciences (JNDS) is now available to read.

New Cochrane evidence explores treatment options for chronic ear disease

A new Evidently Cochrane blog post for World Hearing Day summarises seven recent reviews on medical treatments for infection and inflammation of the middle ear.

New reporting guidelines to bridge the gap from development to implementation in clinical artificial intelligence

In a correspondence to Nature Medicine, a team of Oxford-led academics describe upcoming new guidelines to improve the reporting of early clinical stage (or first-with-human) evaluation of decision support systems driven by artificial intelligence.

Cochrane ENT awarded NIHR funding for COVID-19 project

Cochrane ENT at the Nuffield Department of Surgical Sciences has been awarded funding by the National Institute for Health Research (NIHR) to complete a suite of living systematic reviews investigating the effectiveness and safety of interventions to prevent and treat loss of smell after COVID-19 infection.

Blog posts

Celebrating women of NDS

To celebrate 100 years since women were admitted as full members of the University and on the occasion of International Women's Day, a group of inspirational women in the Nuffield Department of Surgical Sciences (NDS) reflect on their journeys, their place in Medical Sciences and their vision for the next 100 years.

The life of a research nurse: supporting the Oxford COVID-19 Vaccine Trial

Research nurses in the NHS are playing a crucial role in helping to trial new coronavirus treatments and vaccines. Three NDS research nurses stepped up to help with the fight against this new disease. Here Bhumika Patel shares her experience of working on the Oxford COVID-19 Vaccine Trial.

Why I became a Peer Supporter

The Peer Support Programme was developed in recognition of the essential role students play in supporting and encouraging one another on a day-to-day basis throughout their time at university. NDS’ own Helen Stark discusses her experience of becoming a Peer Supporter.

Racism under the microscope

As Black History Month gets underway in the UK, NDS Athena SWAN Coordinator Emily Hotine puts racism under the microscope.

In memory of Sue Bonnington

Pete Holding shares his memories of a much-loved colleague, Sue Bonnington. Based in Leicester, Sue worked remotely for the Nuffield Department of Surgical Sciences (NDS) as a ProtecT study Lead Research Nurse from 2002 to 2017.