Defining the challenges and opportunities for using patient-derived models in prostate cancer research.
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[123I]CC1: A PARP-Targeting, Auger Electron-Emitting Radiopharmaceutical for Radionuclide Therapy of Cancer.
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Imaging DNA damage response by γH2AX in vivo predicts treatment response to Lutetium-177 radioligand therapy and suggests senescence as a therapeutically desirable outcome.
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Imaging PARP with [18F]rucaparib in pancreatic cancer models.
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Know thy tumour: Biomarkers to improve treatment of molecular radionuclide therapy.
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Combination Strategies to Improve Targeted Radionuclide Therapy.
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Imaging DNA Damage Repair In Vivo After 177Lu-DOTATATE Therapy.
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89Zr-PET imaging of DNA double-strand breaks for the early monitoring of response following α- and β-particle radioimmunotherapy in a mouse model of pancreatic ductal adenocarcinoma.
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Imaging DNA Damage in vivo following [177Lu] Lu-DOTATATE therapy in a model of pancreatic neuroendocrine cancer
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O'Neill E. et al, (2019), EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 46, S196 - S196
Drawing on biology to inspire molecular design: a redox-responsive MRI probe based on Gd(iii)-nicotinamide.
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Harnessing the properties of cobalt coordination complexes for biological application
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Hypoxia-Responsive Cobalt Complexes in Tumor Spheroids: Laser Ablation Inductively Coupled Plasma Mass Spectrometry and Magnetic Resonance Imaging Studies.
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O'Neill ES. et al, (2017), Inorg Chem, 56, 9860 - 9868
A cobalt(ii) complex with unique paraSHIFT responses to anions.
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O'Neill ES. et al, (2017), Chem Commun (Camb), 53, 3571 - 3574
Reversible magnetogenic cobalt complexes
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Luminescent Lanthanoid Probes
Chapter
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