Contact information
LOCATION:
Institute of Developmental and Regenerative Medicine, Old Road Campus, Oxford OX3 7TY
John Radcliffe Hospital, Level 6, Headley Way, Headington, Oxford, OX3 9DU
Research groups
Colleges
Fadi Issa
DPhil FRCS(Plast)
Professor of Transplantation, Associate Head & Surgical Sciences Theme Lead
- Consultant Plastic, Reconstructive and Burns Surgeon
- Governing Body Fellow, Green Templeton College
- Academic Lead for Research Funding, Medical Sciences Division
I am Professor of Transplantation at the University of Oxford and a consultant surgeon. My work focuses on turning immunological insight into practical therapies that improve outcomes after organ and cell transplantation, and on broadening the use of immune targeted treatments in inflammatory and immune mediated disease. I integrate mechanistic immunology, biomarker and tissue based human studies, and early phase clinical trials, with a consistent emphasis on safety, durability, and real world implementation.
The Translational Research Immunology Group (TRIG) brings together graduate students, postdoctoral researchers, and clinical academics working across immunology, transplantation, tissue repair, and data driven translational science. We develop and test cellular and immunomodulatory therapies, and use deep immune profiling to understand mechanisms of response, resistance, and long term benefit. Our approach maintains a clear line of sight from discovery to patient impact.
Within Oxford, I serve as Associate Head of Department in the Nuffield Department of Surgical Sciences as Theme Lead for Surgical Sciences. I am also MSD Academic Lead for Research Funding and a Governing Body Fellow at Green Templeton College.
I am Editor in Chief of BMJ Immunology and an Executive Editor of Transplantation. I serve on the Steering Committee of FOCIS and previously chaired The Transplantation Society’s Transplantation Science Committee.
I am committed to building a rigorous and supportive training environment for early career researchers and clinicians, and welcome enquiries from prospective students, fellows, and collaborators.
Recent publications
Tolerance meets regenerative medicine: A new route to donor-specific allograft acceptance?
Journal article
Jull P. and Issa F., (2026), Am J Transplant, 26, 1519 - 1521
Population Viral Load Suppression and Associated Factors in Tanzania: Findings From 2 Sequential Tanzania HIV Impact Surveys of 2016-2017 and 2022-2023.
Journal article
Ismail A. et al, (2026), J Acquir Immune Defic Syndr, 101, 733 - 739
People in Transplantation: Professor Nadey Hakim, MD, PhD, FRCS, FRCSGlas (Hon), FACS, President-Elect of The Transplantation Society.
Journal article
Issa F., (2026), Transplantation
Anita Chong, PhD, Professor of Surgery, University of Chicago.
Journal article
Issa F. and Chong A., (2026), Transplantation
Clinical development of tacrolimus-resistant regulatory T cells to enable simultaneous immunosuppression and immune regulation.
Journal article
Zarrinrad G. et al, (2026), Mol Ther Adv, 34
Protocol for a phase I single-centre dose escalation trial of autologous thymus derived regulatory T cells in paediatric heart transplant recipients to prevent cardiac allograft vasculopathy (ATT-Heart).
Journal article
Aiyengar A. et al, (2026), BMJ Open, 16
Conventional type-1 DC density is associated with checkpoint inhibitor response across multiple types of cancer.
Journal article
Lopez-Janeiro A. et al, (2026), J Clin Invest, 136
Coordinated Terror Attacks and Health Care Facilities: Future Considerations and Implications for Hospital Preparedness and Response-A Scoping Review.
Journal article
Boukai A. et al, (2026), Disaster Med Public Health Prep, 20
Vortex-actuated pre-enrichment accelerates human regulatory T cell sorting and improves early fitness.
Journal article
Ho QY. et al, (2026), Mol Ther Adv, 34
TCR T cells targeting IgA- and IgG-expressing multiple myeloma.
Journal article
Douvlataniotis K. et al, (2026), Blood