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LOCATION:

John Radcliffe Hospital, Level 6, Headley Way, Headington, Oxford, OX3 9DU

DPHIL START DATE

4 October 2021

PROJECT TITLE

A pilot study in high intensity focused ultrasound ablation of soft tissue sarcoma and small symptomatic intra-abdominal desmoid tumours

SUPERVISORS

Dr Joanna Hester and Dr Paul Lyon

Megan Jones

MRes in molecular and cellular biology, BSc (Hons) Biochemistry


DPhil student

I am currently a first year DPhil student within the Transplantation Research and Immunology Group (TRIG) under Dr Joanna Hester. My research focuses on the immunological changes with sarcoma ablation using HIFU. Understanding the immunological changes that occur with tumour ablation may allow for an immunotherapy to be developed to improve cancer treatment. 

I obtained a honours degree from the University of Portsmouth in biochemistry, where my undergraduate research project focused on karyotyping tumours in cockle species as an Erasmus+ project at the Universidad de Vigo under the supervision of Dr Juan Pasantes. I then moved to the University of Birmingham to undertake an MRes in molecular and cellular biology with two separate projects, the first of which looking at the immunological changes with age and the similarities seen with immune-mediated inflammatory diseases with Dr Helen McGettrick. I completed a second project with Dr Warwick Dunn as a literature review on the metabolome of food and the use of precision nutrition to mediate disease progression. After completing my MRes I then moved to Oxford Nanopore Technologies where I worked as a scientist, in the pilot projects lab under Dr Jemma Jordan with a focus on SARS-CoV-2 along with other product development and technical writing.