Biography
I graduated from Clare College, Cambridge with Triple First Class Honours in Medical Sciences and obtained Distinctions in Surgery, Obstetrics and Gynaecology, and Pathology. I completed my house jobs and basic surgical training in Addenbrooke's, Papworth and Wycombe General Hospital, then undertook a DPhil in Oxford characterising Colorectal Cancer Stem Cells, working with Professor Sir Walter Bodmer and Professor Neil Mortensen. Following a post-doctoral fellowship at Stanford University, I started my academic clinical lectureship and higher surgical training in the Oxford Deanery in 2011.
selected Awards
1999 James D Watson Fund Research Scholar, Cold Spring Harbor Laboratory, USA
1999 Clare College Scholarship
1999 George Graham Prize
2000 Burroughs Wellcome Fund Research Scholar, Cold Spring Harbor Laboratory, USA
2000 Clare College Foundation Scholarship
2001 William Butler Prize for Medical Sciences, Clare College
2001 PPP Healthcare Award, Cambridge University Clinical School
2003 Clare College Prize for outstanding performance in Finals
2007 Domus Merit Award, Green Templeton College, University of Oxford
2007 Cancer Research UK Clinical Research Fellowship
2008 Research Fellowship, Royal College of Surgeons of England
2009 Sir Alan Parks Research Fellowship, Royal College of Surgeons of England
2009 Royal Society of Medicine Travelling Fellowship
2013 Harry E Bacon Foundation Award - Best Basic Science Podium Presentation at ASCRS (American Society for Colon and Rectal Surgeons) Annual Meeting, Phoenix, USA
2014 Goodger Scholarship, University of Oxford
Colleges
Websites
Trevor Yeung
MA (Cantab), MBBChir, MRCS, DPhil
Clinical Lecturer
- Fluorescence Image Guided Surgery
- Robotic Surgery
My research focuses on the biology of colorectal cancer to help the diagnosis and treatment of this condition.
More than 40,000 patients in the UK are diagnosed with colorectal cancer each year, and approximately 55% of patients survive this type of cancer for five years or more.
My research interest is clinical translational research, in particular, Fluorescece Image Guided Surgery (FIGS). We are developing new techniques to identify normal anatomy and abnormal pathology during surgery which can help guide surgeons during procedures.
funding
Academy of Medical Sciences - Starter Grant for Clinical Lecturers
Bowel Disease Research Foundation
MRC - Developmental Pathway Funding Scheme (DPFS)
Key publications
Regulation of self-renewal and differentiation by the intestinal stem cell niche.
Journal article
Yeung TM. et al, (2011), Cell Mol Life Sci, 68, 2513 - 2523
dvances in endoscopic visualization of colorectal polyps.
Journal article
Yeung TM. and Mortensen NJ., (2011), Colorectal Dis, 13, 352 - 359
Hypoxia and lineage specification of cell line-derived colorectal cancer stem cells.
Journal article
Yeung TM. et al, (2011), Proc Natl Acad Sci U S A, 108, 4382 - 4387
Cancer stem cells from colorectal cancer-derived cell lines.
Journal article
Yeung TM. et al, (2010), Proc Natl Acad Sci U S A, 107, 3722 - 3727
Colorectal cancer stem cells.
Journal article
Yeung TM. and Mortensen NJ., (2009), Dis Colon Rectum, 52, 1788 - 1796
Recent publications
Fluorescence imaging in colorectal surgery.
Journal article
Yeung TM., (2021), Surg Endosc, 35, 4956 - 4963
Intraoperative identification and analysis of lymph nodes at laparoscopic colorectal cancer surgery using fluorescence imaging combined with rapid OSNA pathological assessment.
Journal article
Yeung TM. et al, (2018), Surg Endosc, 32, 1073 - 1076
Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture.
Journal article
Li X. et al, (2014), Nat Med, 20, 769 - 777
Waist circumference and waist/hip ratio are better predictive risk factors for mortality and morbidity after colorectal surgery than body mass index and body surface area.
Journal article
Kartheuser AH. et al, (2013), Ann Surg, 258, 722 - 730
Stem cell differentiation and lumen formation in colorectal cancer cell lines and primary tumors.
Journal article
Ashley N. et al, (2013), Cancer Res, 73, 5798 - 5809
Quality analysis of patient information on surgical treatment of haemorrhoids on the internet.
Journal article
Yeung TM. and D'Souza ND., (2013), Ann R Coll Surg Engl, 95, 341 - 344
Myofibroblast activation in colorectal cancer lymph node metastases.
Journal article
Yeung TM. et al, (2013), Br J Cancer, 108, 2106 - 2115
Oligodendrocyte progenitor cells: a missed opportunity.
Journal article
Watson RA. et al, (2012), J Neurotrauma, 29, 2593 - 2594
The management of acute spinal cord injury: What the future holds
Journal article
Watson RA. et al, (2012), 89 - 121
ssessment of the quality of patient-orientated Internet information on surgery for diverticular disease.
Journal article
Yeung TM. and Mortensen NJ., (2012), Dis Colon Rectum, 55, 85 - 89