Jessica Scaife
PhD
Research Manager
I have over twenty years experience designing experimental paradigms. A Neuropsychopharmacologist and Cognitive Neuroscientist, my research combines neuroimaging, electrophysiology and stimulation to investigate the neural and pharmacological basis of reward and emotion. During my 20 year postdoctoral career, I investigated brain function in both patient populations and healthy volunteers, using MRI and MEG. I ran studies in experimental medicine, Phase 1 and 3 clinical trials, including deep brain stimulation with Alex Green. I use mixed methods research to capture the lived experience of patients.
A member of the MSD PPI network, I lead PPI throughout trial development, and beyond, I am committed to developing and fostering greater connections with patient partners and charities.
I am passionate about public engagement and encouraging students to consider careers in STEM through events and work experience.
Recent publications
Cost Effectiveness of Local Anaesthetic Transperineal Versus Transrectal Biopsy: Results from the TRANSLATE Study.
Journal article
Little M. et al, (2025), Eur Urol Focus
Prepectoral no mesh versus mesh immediate implant-based reconstruction after mastectomy (Restore-B): a multicentre single-blinded randomised controlled feasibility study protocol.
Journal article
Rolph R. et al, (2025), BMJ Open, 15
Local anaesthetic transperineal biopsy versus transrectal prostate biopsy in prostate cancer detection (TRANSLATE): a multicentre, randomised, controlled trial.
Journal article
Bryant RJ. et al, (2025), Lancet Oncol, 26, 583 - 595
Effects of ulotaront on brain circuits of reward, working memory, and emotion processing in healthy volunteers with high or low schizotypy.
Journal article
Perini F. et al, (2023), Schizophrenia (Heidelb), 9
Catechol-O-methyltransferase activity does not influence emotional processing in men.
Journal article
Martens MA. et al, (2022), J Psychopharmacol, 36, 768 - 775